Hypertension: It is recommended to use losartan potassium to treat hypertension. It could be used with other antihypertensive medications or taken alone (eg. thiazide diuretics). Renal Protection in Type-2 Diabetic Patients with Proteinuria: In hypertensive type-2 diabetics with proteinuria, which is defined as urine albumin to creatinine ratio >300 mg/g, losartan potassium is advised to postpone the advancement of renal disease.

Angiotensin-ll receptor blocker

The first angiotensin II receptor blocker that is orally active without a peptide is losartan potassium. It binds to the AT1 receptor, which is present in numerous tissues (such as the heart, kidneys, adrenal glands, and vascular smooth muscle), and inhibits several critical biological processes, such as vasoconstriction and the production of the hormone aldosterone that causes hypertension.

For the majority of patients, the beginning and maintenance dose is 50 mg once daily. Prior to raising the dose, 25 mg twice daily is advised if the antihypertensive impact of 50 mg once daily is insufficient. A starting dose of 25 mg once daily should be taken into consideration for individuals with intravascular volume depletion (such as those on high-dose diuretics). One or two doses of losartan potassium can be given each day. From 25 mg to 100 mg is the range for the total daily dose.

Levels of the Losartan Potassium active metabolite are decreased by rifampicin and fluconazole. The antihypertensive effects of hydrochlorothiazide and losartan potassium used together may be potentiated. Increases in serum potassium may result from the concurrent use of potassium-sparing diuretics (such as spironolactone, triamterene, and amiloride), potassium supplements, or salt substitutes containing potassium. The non-steroidal anti-inflammatory medicine indomethacin may lessen the antihypertensive effects of losartan. The risk of renal impairment is increased by the concurrent use of an ACE inhibitor, an angiotensin receptor antagonist, an anti-inflammatory medication, and a thiazide diuretic.

Pregnant women and individuals who are hypersensitive to any ingredient in this medication should not use losartan potassium. Those with diabetes shouldn't take Aliskiren and Losartan Potassium together.

Losartan Potassium side effects are minor and short-lived in nature. Dizziness, diarrhea, nasal congestion, coughing, and upper respiratory infections are the most frequent adverse effects. Fatigue, oedema, chest pain, nausea, headaches, and pharyngitis are other adverse effects.

Category D for pregnancies. If Losartan Potassium is given during the second or third trimester of pregnancy, the risk to the fetus increases. Given that numerous medicines are excreted in human milk and that it is unknown whether losartan potassium is one of them, a choice should be taken regarding whether to stop breastfeeding or stop taking the medication, taking into account the significance of the medication to the mother.

In addition to increasing fetal and neonatal morbidity and mortality, the use of losartan potassium throughout the second and third trimesters of pregnancy decreases fetal renal function. Symptomatic hypotension may happen in people who are intravascularly volume-depleted (such as those taking high-dose diuretics). Patients with cirrhosis have a considerably higher plasma concentration of losartan potassium. Patients with renal impairment have experienced changes in renal function, including renal failure.

Keep dry and away from heat and light. Keep out of children's reach.

Angiotensin-ll receptor blocker

The first angiotensin II receptor blocker that is orally active without a peptide is losartan potassium. It binds to the AT1 receptor, which is present in numerous tissues (such as the heart, kidneys, adrenal glands, and vascular smooth muscle), and inhibits several critical biological processes, such as vasoconstriction and the production of the hormone aldosterone that causes hypertension.

Category D for pregnancies. If Losartan Potassium is given during the second or third trimester of pregnancy, the risk to the fetus increases. Given that numerous medicines are excreted in human milk and that it is unknown whether losartan potassium is one of them, a choice should be taken regarding whether to stop breastfeeding or stop taking the medication, taking into account the significance of the medication to the mother.

Related Medicines